Bismuth Triflate Catalyzed Allylation of Acetals: A Simple and Mild Method for Synthesis of Homoallyl Ethers
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چکیده
The allylation of acetals using allyltrimethylsilane is efficiently catalyzed by bismuth triflate (1.0 mol%). The reaction proceeds smoothly at room temperature to afford the corresponding homoallyl ether in good yield. The mild reaction conditions, the low toxicity of bismuth salts, and the high catalytic efficiency of the system make this procedure particularly attractive for large-scale synthesis.
منابع مشابه
Microwave-assisted allylation of acetals with allyltrimethylsilane in the presence of CuBr.
We describe the first synthesis of homoallyl ethers from acetals and allyltrimethylsilane using microwave heating and CuBr as a promoter. This method works best for aromatic acetals, giving the corresponding homoallyl ethers in good to quantitative yield.
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تاریخ انتشار 2017